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GLP-1 and peptide medicines · Checked

Side effects vs placebo, out of 100 people

In trials, people on placebo report some of the same problems. Placebo means a shot with no medicine in it.

Or pick a medicine and side effect

All side effects

Stomach and gut

Whole body

Skin, hair, and shot site

Other

Example: nausea in the Wegovy label

Each dot is 1 in 100 people.

Reported it Rest of a dose range Did not report it

Filled dots show the low end of a range. Dots are rounded. The exact number is above each grid.

WegovyFDA-approved product

Wegovy trials in adults with obesity or overweight

Row in the source: Nausea

Placebo16%
On Wegovy44%
Who was studied
Adults with obesity or overweight in 3 trials. 2,116 got Wegovy and 1,261 got placebo. 19% had type 2 diabetes.
How long
Up to 68 weeks
Source
Wegovy prescribing information on DailyMed . FDA label revised June 2026.

See nausea in every table

How to read the dots

  1. Compare the drug column with the placebo column. Some problems happen without any drug.
  2. A number in a table is the share of people in a study who reported a problem. It is not your own chance of having it.
  3. Check who was studied. People in a trial may differ from you in age, health, and other medicines.

How long were people watched?

Each bar is one set of trials. The dots on this page come only from the time inside each bar.

Stated length Range in the source Some people only No end date given

  1. Egrifta, adults with HIV26 weeks

  2. Forteo, adults with osteoporosis11 months (men), 19 months (women)

  3. Mounjaro, adults with type 2 diabetes40 weeks

  4. Ozempic, adults with type 2 diabetes30 weeks

  5. Saxenda, adults32 to 56 weeks, some up to about 3 years

  6. Saxenda, teens56 weeks

  7. Tymlos, women18 months

  8. Tymlos, men12 months

  9. Victoza, adults with type 2 diabetesAt least 26 weeks each

  10. Vyleesi, women24 weeks

  11. Wegovy, adultsUp to 68 weeks

  12. Wegovy, teens68 weeks

  13. Zepbound, adultsUp to 72 weeks

  14. Cagrilintide, phase 226 weeks of treatment, side effects counted to week 32

  15. Retatrutide, TRIUMPH-180 weeks

  16. Retatrutide, TRIUMPH-280 weeks

  17. Retatrutide, TRIUMPH-380 weeks

  18. Retatrutide, phase 2 (obesity)48 weeks

  19. Retatrutide, phase 2 (diabetes)36 weeks

Trials can miss rare harms and harms that take years to appear.

Where the numbers come from

Every number is copied from a table on our side effect pages. Those tables come from FDA labels on DailyMed, results posted on ClinicalTrials.gov, and company trial results. We did not add, total, or rank any number. Rows keep one fixed order: FDA-approved medicines first, then the rest, each in A to Z order.

We group rows by name. For example, “Tiredness (fatigue)” and “Tiredness or weakness (fatigue)” are both under tiredness. Each row still shows its own words from the source.

The tables on this site copy part of each label, such as the most common problems. A problem missing from one table may still have happened.

Report a side effect

You can report a suspected side effect to the FDA at 1-800-FDA-1088 or through FDA MedWatch . If a reaction feels serious, get medical care first.

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