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Evidence brief

AOD-9604

Written and source-checked by Anthony Treviso, founder of The Peptide Field.

Direct answer

No FDA-approved AOD-9604 drug product.

A modified piece of growth hormone studied in obesity programs. It has no approved use and unresolved route, product, and safety questions.

How strong is the evidence?
Insufficient
Reliable studies in people are missing, too limited, or do not support the claim. This does not prove that the substance has no effect on the body.
What evidence exists?
Investigational human outcomes
Studies measured health results in people, but the molecule is still being studied and is not approved for that use. Important questions remain.
Sports rules
Prohibited
The checked rules list this substance or group as prohibited under the stated conditions. Check the current rules for your sport.

Reviewed July 23, 2026. Sources and update notes are below.

No sales or dosing advice. This guide explains research. It was not independently medically reviewed, and it does not diagnose, prescribe, or recommend treatment.

Also known as AOD9604 · lipotropin · hGH fragment 176-191

Part of Metabolic peptide medicines

Words used here

route
how the product enters the body
investigational
still being studied and not approved for that use
outcome
what the study measured
molecule
one specific chemical substance
compounded
made for one patient by a pharmacy, or in batches by a permitted outsourcing facility; a compounded drug is not FDA-approved
amino acid
a small building block that makes peptides and proteins
indication
the approved or studied use and patient group
More detailProduct and study details

01 · Evidence profile

Four questions about the evidence

Benefits in peopleDid people have a meaningful health benefit?
LimitedThe evidence is too small, indirect, or incomplete for a clear answer.

Older obesity studies exposed hundreds of participants, but the evidence did not establish an approved weight-loss use.

Body changes in peopleDid a study measure how it changed the body in people? This alone does not show a health benefit.
LimitedThe evidence is too small, indirect, or incomplete for a clear answer.

FDA found insufficient pharmacokinetic and pharmacodynamic information for proposed uses and routes.

Known risksHow much do studies tell us about risks in people?
LimitedThe evidence is too small, indirect, or incomplete for a clear answer.

Clinical safety reporting is incomplete, and FDA identifies immunogenicity and impurity concerns.

Exact productHow certain are the product identity and quality?
UnclearThe product identity, evidence, or reporting is not reliable enough to judge.

Identity, route, formulation, sterility, and comparability of compounded products are uncertain.

02 · Identity

What it is

AOD-9604 is a modified piece of human growth hormone, related to amino acids 176-191. It is not full-length growth hormone.

Scientific group: Modified growth-hormone fragment. This group name describes the type of molecule or body signal. It does not prove a benefit, safety, or approval.

03 · Exact product

The molecule is not the finished product.

Formulation: The finished product's ingredients and physical form. Route: How the product enters the body. Indication: The approved or studied use and group of people for a product.

Approved products

None identified in the United States.

Approved or reviewed uses
  • No FDA-approved indication

04 · Research results

What the research shows

What the evidence shows

FDA reviewed several obesity studies in people, including larger oral programs, and documented the available adverse-event reporting. This confirms that people received it in studies. It does not establish a benefit.

What remains unknown

The record does not establish meaningful weight loss, long-term benefit, or safety for injectable or transdermal products. FDA found no human information for some proposed routes of use.

Exact product

A study product, an injection, and a skin product are not automatically the same. Oral clinical-study material, compounded injections, and transdermal products are not interchangeable. FDA found route-specific evidence gaps.

05 · Claim check

Claims I checked

3 claims checked for this brief.

Clinical outcomesWhat a study measured about people's health, symptoms, or ability to function.

“AOD-9604 has been given to people in clinical studies.”

Supported with scopeThe reviewed evidence supports this exact statement only in the situation described below.

FDA's review describes several human studies, primarily using oral or intravenous routes.

Evidence used
Regulatory or product record. This answer uses an official regulator record or a specific product label.
Limits of this answer
Historical study products and routes described in FDA's review. This answer covers only the named molecule and finished product. It also covers the product form and how people used it. The study limits include who took part, what was used for comparison, what changed, and how long the study lasted.
Open the full claim record ↗
Body compositionWhat research measured about body fat, lean mass, or related body changes.

“Human exposure proves AOD-9604 is an effective fat-loss drug.”

MisleadingThis statement leaves out a limit that changes its meaning.

Exposure and tolerability data do not establish a clinically meaningful weight-loss outcome.

Evidence used
No reliable human outcome evidence. No reliable study in people shows the health outcome in this statement.
Limits of this answer
Weight-loss efficacy, not merely participation in a study. This answer covers only the named molecule and finished product. It also covers the product form and how people used it. The study limits include who took part, what was used for comparison, what changed, and how long the study lasted.
Open the full claim record ↗
SafetyWhat is known and not known about harm, warnings, and safety limits.

“Injectable AOD-9604 has a well-characterized safety profile.”

Not establishedThe reviewed evidence does not establish this statement. This does not prove it can never be true.

FDA identifies limited safety data, immunogenicity concerns, and missing information for proposed injectable use.

Evidence used
Regulatory or product record. This answer uses an official regulator record or a specific product label.
Limits of this answer
Compounded injectable AOD-9604. This answer covers only the named molecule and finished product. It also covers the product form and how people used it. The study limits include who took part, what was used for comparison, what changed, and how long the study lasted.
Open the full claim record ↗

06 · Questions

Questions people ask about AOD-9604

Is AOD-9604 FDA approved?

No FDA-approved AOD-9604 drug product. No approved product is identified in the United States.

Is AOD-9604 banned in sport?

Prohibited. AOD-9604 is named as a prohibited growth-hormone fragment on the 2026 WADA Prohibited List. This status is not personal clearance to compete.

What does the evidence show for AOD-9604?

FDA reviewed several obesity studies in people, including larger oral programs, and documented the available adverse-event reporting. This confirms that people received it in studies. It does not establish a benefit.

What is still unknown about AOD-9604?

The record does not establish meaningful weight loss, long-term benefit, or safety for injectable or transdermal products. FDA found no human information for some proposed routes of use.

07 · Safety

Safety limits for this record

An incomplete development program does not provide instructions for self-treatment. No sourcing, reconstitution, injection, or weight-loss regimen is provided.

Sports rules · Prohibited

AOD-9604 is named as a prohibited growth-hormone fragment on the 2026 WADA Prohibited List.

The checked rules list this substance or group as prohibited under the stated conditions. Check the current rules for your sport.

Reviewed .Check current rules for tested sport ↗Open the governing record ↗

08 · Sources

Read the sources

09 · Review history

Review history

Initial brief based on FDA's 2024 compounding review and current safety-risk page.

Written and source-checked by Anthony Treviso, founder of The Peptide Field.

Not independently medically reviewed. This page is not a dosing, sourcing, or treatment guide.