Claim being checked · Version 1 · Reviewed
“LL-37 is proven to heal wounds in people.”
Written and source-checked by Anthony Treviso, founder of The Peptide Field.
No dosing advice. This guide explains research. It was not independently medically reviewed, and it does not diagnose, prescribe, or recommend treatment.
Not established. The reviewed evidence does not establish this statement. This does not prove it can never be true.
Answer scope
This verdict checks the exact claim in the heading. It is not a universal grade for LL-37.
01 · Answer
Not established
The first 34-person leg-ulcer study reported possible benefit. A later study assigned 149 people to LL-37 or placebo. Of those people, 148 received a study treatment. It found no clear benefit for the full group. A 25-person diabetic-foot-ulcer study found a limited sign of new tissue growth, but no clear changes in other measures. These results do not prove general wound healing.
- What kind of evidence this is
- Randomized human outcomes. This answer uses a study that assigned people to groups by chance and measured a health outcome.
- What this answer covers
- The reviewed venous-ulcer studies and small diabetic-foot-ulcer study; results apply only to their defined products, groups, wound types, and follow-up periods. This answer covers only the named molecule and finished product. It also covers the product form and how people used it. The study limits include who took part, what was used for comparison, what changed, and how long the study lasted.
- Question type
- Clinical outcomes. What a study measured about people's health, symptoms, or ability to function.
02 · Sources
Read the sources behind this answer
Defines the evidence limit02Later randomized trial of LL-37 in venous leg ulcersPubMed · Randomized trial · 2021
Defines the evidence limit03Randomized study of topical LL-37 in diabetic foot ulcersPubMed · Randomized trial · 2023
Defines the evidence limit
- Editorial review
- Internal editorial review recorded
- Source review
- Anthony Treviso · Founder and responsible editor
- Medical review status
- Not independently medically reviewed. Editorial source review does not replace medical review.