{ "schemaVersion": "2.1", "datasetVersion": "2026-09-11.1", "generatedAt": "2026-09-11", "reviewStatus": "Editorial source review is complete. This edition has not been independently medically reviewed.", "editorialBoundary": "Source-checked educational summaries. Topics require evidence and editorial review. This dataset is not a personal treatment plan.", "citation": "When you cite a record, include The Peptide Field, its canonicalPath, this dataset version, and every source used for the claim.", "reuse": "This endpoint grants no additional reuse license. Keep the verdict, scope, evidence basis, review date, and source links together. Do not present a record as medical advice or medical review.", "changeLogPath": "/corrections#correction-ledger", "contactPath": "/corrections", "dataset": "peptide-evidence-checker-record", "canonicalPath": "/peptides/bpc-157", "canonicalUrl": "https://thepeptidefield.com/peptides/bpc-157", "record": { "slug": "bpc-157", "name": "BPC-157", "className": "Synthetic pentadecapeptide", "sequenceLabel": "15 amino acids · investigational", "tier": "Emerging", "statusLine": "Still being studied; no FDA-approved BPC-157 product identified", "profile": { "humanOutcomes": { "level": "Limited", "note": "Small uncontrolled pilots cannot establish a patient benefit." }, "humanPharmacology": { "level": "Limited", "note": "Human exposure and pharmacokinetic characterization remain sparse." }, "safetyKnowledge": { "level": "Limited", "note": "The human safety dataset is too small for confident risk estimates." }, "productCertainty": { "level": "Unclear", "note": "No validated approved formulation; identity and purity vary outside formal research." } }, "oneLine": "Cell and animal studies, plus small early studies in people, do not prove that BPC-157 heals injuries in people.", "reviewedAt": "July 23, 2026", "whatItIs": "Online popularity is not proof that a treatment works. BPC-157 is a synthetic 15-amino-acid peptide promoted online for injury recovery and other uses. Popularity, testimonials, animal findings, and availability are not evidence of an approved or proven human treatment.", "whatWeKnow": "The preclinical literature contains positive signals in cell and animal models, including tendon-healing models. Small human pilot work and registered clinical research now exist, but do not establish a clinical effect in people. FDA's July 2026 PCAC briefing evaluated BPC-157-related bulk substances for a nominated ulcerative-colitis use and documented evidence and safety gaps. That advisory-stage record supports scrutiny; it is not a final FDA determination.", "whatWeDoNotKnow": "The available evidence still does not establish that BPC-157 safely heals sports injuries or other conditions in people. Early, uncontrolled, or registered research is not the same as a replicated patient benefit, and a trial listing is not a positive result.", "safetyBoundary": "The site will not provide self-injection, reconstitution, dosing, sourcing, or stack instructions. “Research use only” does not establish quality or make a product appropriate for human use.", "claims": [ { "claim": "“BPC-157 improves tendon healing in preclinical models.”", "verdict": "Supported with scope", "explanation": "Cell and rat tendon studies report positive healing signals. The scope matters: these results support biological plausibility, not a proven human treatment.", "category": "Performance and recovery", "evidenceBasis": "Preclinical evidence", "scope": "Cell and animal tendon models only; not clinical healing outcomes in people.", "sourceUrls": [ "https://pubmed.ncbi.nlm.nih.gov/21030672/" ] }, { "claim": "“BPC-157 heals tendons and muscles in people.”", "verdict": "Not established", "explanation": "Early human work is too small and limited to establish efficacy. Reliable, replicated human outcome evidence is still needed.", "category": "Performance and recovery", "evidenceBasis": "No reliable human outcome evidence", "scope": "Human tendon and muscle-healing claims; existing pilots and a trial registration do not establish benefit.", "sourceUrls": [ "https://pubmed.ncbi.nlm.nih.gov/42198317/", "https://pubmed.ncbi.nlm.nih.gov/40131143/", "https://clinicaltrials.gov/study/NCT07437547" ] }, { "claim": "“Athletes can use it because it is not a steroid.”", "verdict": "Misleading", "explanation": "The 2026 WADA Prohibited List places BPC-157 in S0 non-approved substances, which is prohibited at all times for covered athletes. Whether it is a steroid is irrelevant to that status.", "category": "Performance and recovery", "evidenceBasis": "Regulatory or product record", "scope": "Athletes subject to the current WADA Code and their applicable governing-body rules.", "sourceUrls": [ "https://www.wada-ama.org/en/resources/world-anti-doping-program/prohibited-list" ] } ], "sources": [ { "label": "July 2026 PCAC briefing on BPC-157-related bulk drug substances", "publisher": "U.S. Food and Drug Administration", "url": "https://www.fda.gov/media/193343/download", "kind": "FDA review", "year": 2026, "accessedAt": "2026-07-23" }, { "label": "Certain bulk drug substances for use in compounding that may present significant safety risks", "publisher": "U.S. Food and Drug Administration", "url": "https://www.fda.gov/drugs/human-drug-compounding/certain-bulk-drug-substances-use-compounding-may-present-significant-safety-risks", "kind": "Regulatory", "year": 2026, "accessedAt": "2026-07-23" }, { "label": "BPC-157 as an investigational peptide therapeutic: translational development barriers", "publisher": "PubMed · Pharmaceutics", "url": "https://pubmed.ncbi.nlm.nih.gov/42198317/", "kind": "Science review", "year": 2026, "accessedAt": "2026-07-23" }, { "label": "Safety of intravenous infusion of BPC157 in humans: a pilot study", "publisher": "PubMed · Alternative Therapies in Health and Medicine", "url": "https://pubmed.ncbi.nlm.nih.gov/40131143/", "kind": "Human pilot", "year": 2025, "accessedAt": "2026-07-23" }, { "label": "Promoting effect of BPC 157 on tendon healing: tendon outgrowth, cell survival, and migration", "publisher": "PubMed · Journal of Applied Physiology", "url": "https://pubmed.ncbi.nlm.nih.gov/21030672/", "kind": "Preclinical", "year": 2011, "accessedAt": "2026-07-23" }, { "label": "2026 prohibited list", "publisher": "World Anti-Doping Agency", "url": "https://www.wada-ama.org/en/resources/world-anti-doping-program/prohibited-list", "kind": "Anti-doping", "year": 2026, "accessedAt": "2026-07-23" }, { "label": "BPC 157 for acute hamstring muscle strain repair", "publisher": "ClinicalTrials.gov", "url": "https://clinicaltrials.gov/study/NCT07437547", "kind": "Trial registry", "year": 2026, "accessedAt": "2026-07-23" } ], "aliases": [ "BPC 157", "Body Protection Compound 157", "pentadecapeptide BPC 157" ], "family": "Recovery and repair claims", "evidenceContext": "Investigational human outcomes", "productContext": "A peptide sequence, a nominated bulk substance, a clinical-study product, and a consumer vial are separate evidence objects. Identity and product quality cannot be assumed from the name.", "approvedProducts": [], "productRecords": [], "indications": [ "No FDA-approved indication" ], "reviewedAtISO": "2026-08-01", "reviewHistory": [ { "date": "2026-08-01", "note": "Revalidated BPC-157's S0 prohibited-at-all-times status against the 2026 WADA Prohibited List." }, { "date": "2026-07-23", "note": "Updated around FDA's July 2026 briefing and explicit product-identity boundaries." } ], "antiDoping": "BPC-157 is prohibited under WADA's non-approved substances category. Athletes should use the current list and their governing body's rules.", "antiDopingReview": { "status": "Prohibited", "detail": "BPC-157 is listed under WADA's S0 non-approved substances category and is prohibited at all times for covered athletes.", "sourceUrl": "https://www.wada-ama.org/en/resources/world-anti-doping-program/prohibited-list", "reviewedAtISO": "2026-08-01" }, "relatedSlugs": [ "tb-500", "ghk-cu", "ipamorelin" ] } }